• Short term changes in the proteome of human cerebral organoids induced by 5-MeO-DMT

    Here we used shotgun mass spectrometry to explore proteomic differences induced by 5-methoxy-N,N-dimethyltryptamine (5-MeO-DMT) on human cerebral organoids. Out of the 6,728 identified proteins, 934 were found differentially expressed in 5-MeO-DMT-treated cerebral organoids.
  • Multiple Stages of Memory Formation and Persistence

    The idea that memories are not made instantly after learning but need to undergo a time-dependent, metabolically active complex consolidation process before they can be stably stored has dominated the neuroscience of learning and memory for decades.
  • Sleep, Synaptic Plasticity, and Memory

    The mechanisms underlying the intimate connection between sleep and learning are becoming increasingly clear.
  • Effect of Chronic Stress during Adolescence in Prefrontal Cortex Structure and Function

    We speculate upon the risks of prolonged exposure to stressful environments in human adolescents and the possibility of stunted development of executive functions.
  • Asymmetry of the temporal code for space by hippocampal place cells

    Here we show that the spike timing of place cells couples to theta phase before major increases in firing rate, anticipating the animal’s entrance into the classical, rate-based place field.
  • Place and grid cells in a loop: implications for memory function and spatial coding

    Based on the anatomy of the entorhinal-hippocampal circuitry, we constructed a model of place and grid cells organized in a loop to investigate their mutual influence in the establishment of their codes for space.
  • Comparison of techniques used for functional evaluation of pelvic floor muscles

    Objective: To identify and discuss techniques for evaluation of pelvic floor muscles (PFM) focusing on the most used and accessible techniques in health care.
  • Electrophysiological evidence that the retrosplenial cortex displays a strong and specific activation phased with hippocampal theta during paradoxical (REM) sleep

    It is widely accepted that cortical neurons are similarly more activated during waking and paradoxical sleep (PS, aka REM) than during slow wave sleep (SWS).
  • Unveiling Fast Field Oscillations through Comodulation

    Comodulation analysis unveils four different types of fast LFP activity coupled to theta: two oscillations within the traditional gamma band, HFOs, and spike-leaked activity.
  • Common Marmosets: A Potential Translational Animal Model of Juvenile Depression

  • Transcriptional profile of induced and primary neurons reveals new candidate genes for lineage reprogramming

    We show that the transcriptional profile of a subpopulation of lineage-reprogrammed MEFs resembles that of primary neural progenitors and neurons, indicating that the intermediate steps enacted by reprogramming factors within MEFs during the transition to iNs are similar to those observed during...
  • Lineage Reprogramming of Astroglial Cells from Different Origins into Distinct Neuronal Subtypes

    We show that cerebellum (CerebAstro) and cerebral cortex astroglia (CtxAstro) generates iNs with distinctive neurochemical and morphological properties. Both astroglial populations contribute iNs to the olfactory bulb following transplantation in the postnatal and adult mouse subventricular zone.