Publications

  • Rapid antidepressant effects of the psychedelic ayahuasca in treatment-resistant depression: a randomized placebo-controlled trial

    06/19/2018
    This study brings new evidence supporting the safety and therapeutic value of ayahuasca, dosed within an appropriate setting, to help treat depression.
  • Direct Reprogramming of Adult Human Somatic Stem Cells Into Functional Neurons Using Sox2, Ascl1, and Neurog2

    06/12/2018
    Here, we show that the expression of the transcription factor SRY (sex determining region Y)-box 2 (Sox2), Ascl1 or Neurog2 is sufficient to lineage-convert a small fraction of human umbilical cord mesenchymal stem cells (hUCMSCs) into iNs.
  • Respiration-Entrained Brain Rhythms Are Global but Often Overlooked

    04/20/2018
    We summarize recent evidence showing that nasal respiration entrains oscillations at the same frequency as breathing in several regions of the rodent brain.
  • Callosal Influence on Visual Receptive Fields Has an Ocular, an Orientation-and Direction Bias

    04/17/2018
    One leading hypothesis on the nature of visual callosal connections (CC) is that they replicate features of intrahemispheric lateral connections. However, CC act also in the central part of the binocular visual field.
  • Instructing neuronal identity during CNS development and astroglial-lineage reprogramming: Roles of NEUROG2 and ASCL1

    03/28/2018
    In this review, we discuss the contribution of the proneural genes Neurogenin2 (Neurog2) and Achaete-scute homolog 1 (Ascl1) for the specification of neuronal phenotypes in the developing neocortex, cerebellum and retina.
  • Motion contrast in primary visual cortex: a direct comparison of single neuron and population encoding

    02/15/2018
    We analyzed firing rates and phase-locking to low-gamma frequency in single cells and neuronal assemblies. Motion contrast was reflected in all measures but in semi-independent populations.
  • Extracting information from the shape and spatial distribution of evoked potentials.

    01/31/2018
    Over 90 years after its first recording, scalp electroencephalography (EEG) remains one ofthe most widely used techniques in human neuroscience research, in particular for the study of event-related potentials (ERPs).
  • Subtle Alterations in Spatial Memory Induced by Amyloid Peptides Infusion in Rats

    01/30/2018
    In the present study, we evaluated the effects of a low-dose 15-day long treatment with Ab peptides on spatial and non-spatial strategies of rats tested in the Barnes maze. Ab peptides (0.5 mL/site/day; 30 pmoL solution of Ab1–40:Ab1–42 10:1) or saline...
  • Specifc Phospholipids Regulate the Acquisition of Neuronal and Astroglial Identities in Post-Mitotic Cells

    01/16/2018
    Embryonic stem cell diferentiation in specifc cell lineages is a major issue in cell biology, and particularly, in regenerative medicine. Neural stem cells (NSCs) have the potential for self-renewal and diferentiation into neurons, astrocytes and oligodendrocytes.
  • Live Imaging Followed by Single Cell Tracking to Monitor Cell Biology and the Lineage Progression of Multiple Neural Populations

    01/16/2018
    Understanding the mechanisms that control critical biological events of neural cell populations, such as proliferation, differentiation, or cell fate decisions, will be crucial to design therapeutic strategies for many diseases affecting the nervous system.
  • The interpretation of dream meaning: Resolving ambiguity using Latent Semantic Analysis in a small corpus of text

    11/07/2017
    Computer-based dreams content analysis relies on word frequencies within predefined categories in order to identify different elements in text.
  • The language of geometry: Fast comprehension of geometrical primitives and rules in human adults and preschoolers

    10/24/2017
    Here, we ask whether a “geometrical language” with recursive embedding also underlies the human ability to encode sequences of spatial locations.