Publications - Neurodynamics

  • Limiting glutamate transmission in a Vglut2-expressing subpopulation of the subthalamic nucleus is sufficient to cause hyperlocomotion

    Our results demonstrate that altering the contribuition of a limited population within the STN is sufficiente to achieve results similar to STN lesions and high-frequecy stimulation, but with fewer side effects.
  • Increased hippocampal excitability and impaired spatial memory function in mice lacking VGLUT2 selectively in neurons defined by tyrosine hydroxylase promoter activity

    These knockout mice showed impairment in spatial memory function. Electrophysiological analyses revealed a profound alteration of oscillatory activity in the CA3 region of the hippocampus.