Cross-frequency phase-amplitude coupling between hippocampal theta and gamma oscillations during recall destabilizes memory and renders it susceptible to reconsolidation disruption
08/24/2020
Our results indicate that hPAC mediates the destabilization required for avoidance memory reconsolidation, and suggest that generation of artificial hPAC at recall overcomes the boundary conditions of this process.
Multiple Stages of Memory Formation and Persistence
10/13/2017
The idea that memories are not made instantly after learning but need to undergo a time-dependent, metabolically active complex consolidation process before they can be stably stored has dominated the neuroscience of learning and memory for decades.
Medial prefrontal cortex dopamine controls the persistent storage of aversive memories.
11/01/2014
Our results indicate that besides its well-known participation in retrieval and early consolidation, mPFC also modulates the endurance of long-lasting aversive memories regardless of whether formation of the aversive mnemonic trace requires the participation of the hippocampus.
State-dependent effect of dopamine D1/D5 receptors inactivation on memory destabilization and reconsolidation
09/03/2014
We found that when given in dorsal CA1 either immediately after training or 15 min before ORM reactivation in the presence of a novel object, the dopamine D1/D5 receptor antagonist SCH23390 did not affect ORM consolidation, expression or retention but impeded the...
Early Activation of Extracellular Signal-Regulated Kinase Signaling Pathway in the Hippocampus is Required for Short-Term Memory Formation of a Fear-Motivated Learning
The molecular cascades of long-term potentiation underlie memory consolidation of one-trial avoidance in the CA1 region of the dorsal hippocampus, but not in the basolateral amygdala or the neocortex
Retinol induces the ERK1/2-dependent phosphorylation of CREB through a pathway involving the generation of reactive-oxygen species in cultured Sertoli cells
Inhibition of hippocampal Jun N-terminal kinase enhances short-term memory but blocks long-term memory formation and retrieval of an inhibitory avoidance task
Learning-associated activation of nuclear MAPK, CREB and Elk-1, along with Fos production in rat hippocampus after a one-trial avoidance learning: abolition by NMDA receptor blockade.