Publications

  • USO DE TRANSPLANTE DE ASTRÓCITOS NA REDUÇÃO DA EPILEPSIA EXPERIMENTAL

    02/28/2018
  • Lithium modulates the muscarinic facilitation of synaptic plasticity and theta-gamma coupling in the hippocampal-prefrontal pathway

    02/16/2018
    Here we investigated the effects of lithium on prefrontal cortex responses under cholinergic drive. Lithium-treated rats were anesthetized with urethane and implanted with a ventricular cannula for muscarinic activation, a recording electrode in the medial prefrontal cortex (mPFC), and a stimulating electrode...
  • Motion contrast in primary visual cortex: a direct comparison of single neuron and population encoding

    02/15/2018
    We analyzed firing rates and phase-locking to low-gamma frequency in single cells and neuronal assemblies. Motion contrast was reflected in all measures but in semi-independent populations.
  • Extracting information from the shape and spatial distribution of evoked potentials.

    01/31/2018
    Over 90 years after its first recording, scalp electroencephalography (EEG) remains one ofthe most widely used techniques in human neuroscience research, in particular for the study of event-related potentials (ERPs).
  • Subtle Alterations in Spatial Memory Induced by Amyloid Peptides Infusion in Rats

    01/30/2018
    In the present study, we evaluated the effects of a low-dose 15-day long treatment with Ab peptides on spatial and non-spatial strategies of rats tested in the Barnes maze. Ab peptides (0.5 mL/site/day; 30 pmoL solution of Ab1–40:Ab1–42 10:1) or saline...
  • Orientation selectivity of neurons and their spatial layout in cat and agouti primary visual cortex.

    01/29/2018
    So far, there is no evidence of a columnar orientation preference map in rodent primary visual cortex, such as commonly observed in carnivores and primates. At the same time, orientation selective neurons have been found in all rodent species investigated, though interspersed....
  • Specifc Phospholipids Regulate the Acquisition of Neuronal and Astroglial Identities in Post-Mitotic Cells

    01/16/2018
    Embryonic stem cell diferentiation in specifc cell lineages is a major issue in cell biology, and particularly, in regenerative medicine. Neural stem cells (NSCs) have the potential for self-renewal and diferentiation into neurons, astrocytes and oligodendrocytes.
  • Live Imaging Followed by Single Cell Tracking to Monitor Cell Biology and the Lineage Progression of Multiple Neural Populations

    01/16/2018
    Understanding the mechanisms that control critical biological events of neural cell populations, such as proliferation, differentiation, or cell fate decisions, will be crucial to design therapeutic strategies for many diseases affecting the nervous system.
  • The interpretation of dream meaning: Resolving ambiguity using Latent Semantic Analysis in a small corpus of text

    11/07/2017
    Computer-based dreams content analysis relies on word frequencies within predefined categories in order to identify different elements in text.
  • The language of geometry: Fast comprehension of geometrical primitives and rules in human adults and preschoolers

    10/24/2017
    Here, we ask whether a “geometrical language” with recursive embedding also underlies the human ability to encode sequences of spatial locations.
  • Short term changes in the proteome of human cerebral organoids induced by 5-MeO-DMT

    10/13/2017
    Here we used shotgun mass spectrometry to explore proteomic differences induced by 5-methoxy-N,N-dimethyltryptamine (5-MeO-DMT) on human cerebral organoids. Out of the 6,728 identified proteins, 934 were found differentially expressed in 5-MeO-DMT-treated cerebral organoids.
  • Multiple Stages of Memory Formation and Persistence

    10/13/2017
    The idea that memories are not made instantly after learning but need to undergo a time-dependent, metabolically active complex consolidation process before they can be stably stored has dominated the neuroscience of learning and memory for decades.