Publications

  • HERDABILIDADE DO COMPORTAMENTO SOCIAL E ALTERAÇÕES NA COMPOSIÇÃO NEURONAL DO CÓRTEX PRÉ-FRONTAL EM UM MODELO ANIMAL DE AUTISMO

    08/10/2018
  • OLMa2 cells bidirectionally modulate learning

    08/03/2018
    Here we set out to determine whether selective modulation of OLMa2 cells in the intermediate CA1 affects learning and memory in vivo.
  • Post-class naps boost declarative learning in a naturalistic school setting

    08/03/2018
    Here we assessed the effect of post-class naps on the retention of Science and History curricular contents presented by the regular class teacher to 24 students from 5th grade. Retention was repeatedly measured 3–4 days after content learning, with weekly group randomization...
  • Memory corticalization triggered by REM sleep: mechanisms of cellular and systems consolidation

    07/30/2018
    This article reviews the plasticity mechanisms triggered by REM sleep, with a focus on the emerging role of kinases and immediate-early genes for the progressive corticalization of hippocampus-dependent memories.
  • Theta-Gamma Cross-Frequency Analyses (Hippocampus)

    07/23/2018
    We found a canonical correlation linking speech connectedness and i) functional as well as developmentally relevant structural brain markers (degree centrality from resting state functional imaging and cortical gyrification index) ii) psychometric evaluation of thought disorder iii) aspects of cognitive performance (processing...
  • Speech structure links the neural and socio-behavioural correlates of psychotic disorders

    07/12/2018
    We found a canonical correlation linking speech connectedness and i) functional as well as developmentally relevant structural brain markers (degree centrality from resting state functional imaging and cortical gyrification index) ii) psychometric evaluation of thought disorder iii) aspects of cognitive performance (processing...
  • Rapid antidepressant effects of the psychedelic ayahuasca in treatment-resistant depression: a randomized placebo-controlled trial

    06/19/2018
    This study brings new evidence supporting the safety and therapeutic value of ayahuasca, dosed within an appropriate setting, to help treat depression.
  • Direct Reprogramming of Adult Human Somatic Stem Cells Into Functional Neurons Using Sox2, Ascl1, and Neurog2

    06/12/2018
    Here, we show that the expression of the transcription factor SRY (sex determining region Y)-box 2 (Sox2), Ascl1 or Neurog2 is sufficient to lineage-convert a small fraction of human umbilical cord mesenchymal stem cells (hUCMSCs) into iNs.
  • Parallel detection of theta and respiration-coupled oscillations throughout the mouse brain

    04/24/2018
    We find that respiration-coupled oscillations can be detected in parallel with theta in several neocortical regions, from prefrontal to visual areas, and also in subcortical structures such as the thalamus, amygdala and ventral hippocampus.
  • Respiration-Entrained Brain Rhythms Are Global but Often Overlooked

    04/20/2018
    We summarize recent evidence showing that nasal respiration entrains oscillations at the same frequency as breathing in several regions of the rodent brain.
  • Callosal Influence on Visual Receptive Fields Has an Ocular, an Orientation-and Direction Bias

    04/17/2018
    One leading hypothesis on the nature of visual callosal connections (CC) is that they replicate features of intrahemispheric lateral connections. However, CC act also in the central part of the binocular visual field.
  • Instructing neuronal identity during CNS development and astroglial-lineage reprogramming: Roles of NEUROG2 and ASCL1

    03/28/2018
    In this review, we discuss the contribution of the proneural genes Neurogenin2 (Neurog2) and Achaete-scute homolog 1 (Ascl1) for the specification of neuronal phenotypes in the developing neocortex, cerebellum and retina.