• Is perception the missing link between creativity, curiosity and schizotypy? Evidence from spontaneous eye-movements and responses to auditory oddball stimuli

    We further compared saliency maps finding that individuals high versus low in creativity and curiosity, respectively, exhibit differences in where they look. These findings may suggest a perception-based link between creativity and curiosity, but not schizotypy. Implications and limitations of these findings...
  • The impact of Ayahuasca on suicidality: results from a randomized controlled trial

    The findings suggest that ayahuasca may show potential as an intervention for suicidality. We highlight important limitations of the study, potential mechanisms, and future directions for research on ayahuasca as an intervention for suicidality.
  • Chrna2-OLM interneurons display different membrane properties and h-current magnitude depending on dorsoventral location

    Thus, our results highlight regional differences in membrane properties between dorsal and ventral OLM cells allowing this interneuron to differently participate in the generation of hippocampal theta rhythms depending on spatial location along the dorsoventral axis of the hippocampus.
  • Hippocampal CA1 and cortical interictal oscillations in the pilocarpine model of epilepsy

    Quantitative electroencephalogram analysis has been increasingly applied to study fine changes in brain oscillations in epilepsy. Here we aimed to evaluate interictal oscillations using pilocarpine model of epilepsy to identify changes in network synchronization.
  • A semi-parametric statistical test to compare complex networks

    The modelling of real-world data as complex networks is ubiquitous in several scientific fields, for example, in molecular biology, we study gene regulatory networks and protein–protein interaction (PPI)_networks; in neuroscience, we study functional brain networks; and in social science, we analyse social...
  • Verbal Short-Term Memory Underlies Typical Development of “Thought Organization” Measured as Speech Connectedness

    Here we set out to test a longitudinal sample (6–8 years old, n =45, followed for 2 years) to verify whether the LSC is predictive of various memory measures, and whether such relations can explain the correlation with reading.
  • Modulation of serum brain-derived neurotrophic factor by a single dose of ayahuasca: observation from a randomized controlled trial

    The results suggest a potential link between the observed antidepressant effects of ayahuasca and changes in serum BDNF, which contributes to the emerging view of using psychedelics as an antidepressant.
  • The GCN2 inhibitor IMPACT contributes to diet-induced obesity and body temperature control

    This phenotype was partially dependent on GCN2, whereas the lean phenotype was independent of GCN2. Taken together, our results indicate that IMPACT contributes to GCN2-dependent and -independent mechanisms involved in the regulation of autonomic functions in response to energy availability.
  • Portable devices to induce lucid dreams — are they reliable?

    One of the main current challenges in lucid dreaming (LD) research is to develop a simple and reliable way to induce it (Stumbrys et al., 2012). This is because, for most people, LD is very pleasurable but also very rare (LaBerge and...
  • On the impact of the pangenome and annotation discrepancies while building protein sequence databases for bacteria proteogenomics

    We show that by using an approach where database size is controlled by removing repeated identical tryptic sequences across strains/species, computational time can be reduced drastically as database complexity increases.
  • comprehensive analysis of core polyadenylation sequences and regulation by microRNAs in a set of cancer predisposition genes

    Herein, we characterized PAS and CS sequences in a set of cancer predisposition genes (CPGs) and performed an in silico investigation of microRNAs (miRNAs) regulation to identify potential tumor-suppressive and oncogenic miRNAs. NCBI and alternative polyadenylation databases were queried to characterize CPE...
  • Can body mass index identify cardiac autonomic dysfunction in women who are apparently healthy?

    We investigated the extent to which obesity could identify autonomic dysfunction of heart control in a cross-sectional study with 65 women (aged 18-45 years), categorized as eutrophic, overweight or obese. We collected anthropometric measures and measures of heart rate variability (HRV) between...