Foto: Gustavo Stephan / Agência O Globo
New insights about brain development using stem cells and brain organoids
Stevens Rehen, D’Or Institute for Research and Education (IDOR) & Institute of Biomedical Sciences, Federal University of Rio de Janeiro, Brazil
Progress has been made regarding the differentiation of human pluripotent stem cells into neural stem cells and astrocytes in 2D and also in 3D cultures, such as cerebral organoids. These organoids recreate some steps of the cerebral cortex development, showing potential for human modeling studies. These models offer an exciting new range of opportunities to investigate the biology of virus infection, cell signaling triggered by psychedelics and brain development. Our recent results will be discussed during this presentation.