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Computational Tracking of Mental Health in Youth: Latin American Contributions to a Low-Cost and Effective Solution for Early Psychiatric Diagnosis

Here, we briefly introduce the problem by reviewing the scarce epidemiological data from Latin America regarding the onset of mental disorders, and discussing the difficulties associated with early diagnosis.
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A Respiration-Coupled Rhythm in the Rat Hippocampus Independent of Theta and Slow Oscillations

Hippocampal respiration rhythm in rats. This work shows that the hippocampus produces two low-frequency rhythms at nearby frequencies: one that couples to respiration and another that is coupled to the neocortex. The results support a role for brain oscillations in connecting distant brain regions, and posit the respiratory cycle as an important reference for neuronal communication between olfactory and memory networks.
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A genetic network that suppresses genome rearrangements in Saccharomyces cerevisiae and contains defects in cancers

Gross chromosomal rearrangements (GCRs) play an important role in human diseases, including cancer. The identity of all Genome Instability Suppressing (GIS) genes is not currently known.
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Human Brain Expansion during Evolution Is Independent of Fire Control and Cooking

What makes humans unique? This question has fascinated scientists and philosophers for centuries and it is still a matter of intense debate. Nowadays, human brain expansion during evolution has been acknowledged to explain our empowered cognitive capabilities. The drivers for such accelerated expansion remain, however, largely unknown. In this sense, studies have suggested that the cooking of food could be a pre-requisite for the expansion of brain size in early hominins.
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Repertoires of Spike Avalanches Are Modulated by Behavior and Novelty

Esse artigo mostra em ratos que avalanches neuronais variam através do ciclo sono vigília e refletem em alguma medida os comportamentos dos animais. Detectamos a existência de repertórios complexos de padrões de ativação entre neurônios (avalanches) que são construídas na vigília e reverberadas/repetidas durante o sono. As repetições podem acontecer com intervalos de muitos minutos, se estendendo por várias horas.
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Motor Coordination Correlates with Academic Achievement and Cognitive Function in Children

The relationship between exercise and cognition is an important topic of research that only recently began to unravel.
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Live Imaging of Adult Neural Stem Cells in Rodents

Adult Neural Stem Cells (NSC) in the mouse subventricular zone (SVZ) tracked by retroviral labeling during embryonic development (GFP, green) and identified by the proliferative (Ki67, blue) and astrocyte-specific marker (GFAP, red).
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Psychosis and the Control of Lucid Dreaming

Dreaming and psychosis share important features, such as intrinsic sense perceptions independent of external stimulation, and a general lack of criticism that is associated with reduced frontal cerebral activity.
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Impaired theta-gamma coupling in APP-deficient mice

The amyloid precursor protein (APP) is critically involved in the pathophysiology of Alzheimer’s disease, but its physiological functions remain elusive. This work shows that lack of APP reduces oscillatory coupling in voltage recordings from specific brain regions, despite not affecting the amplitude of the oscillations, thus pointing to reduced cross-frequency coupling as a functional marker of APP deficiency at the network level.
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Hippocampal Respiration-Driven Rhythm Distinct from Theta Oscillations in Awake Mice

This work demonstrates that the hippocampus of awake mice produces slow oscillations that are entrained by nasal respiration. The rhythm is close in frequency to, but distinct from, classical theta oscillations. The results suggest that respiration-coupled oscillations aid the exchange of information between olfactory and memory networks.
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Grid Cells and Place Cells: An Integrated View of their Navigational and Memory Function

This model explains why MEC lesions can abolish hippocampal phase precession but not place fields.
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Impaired Processing in the Primary Auditory Cortex of an Animal Model of Autism

Autism is a neurodevelopmental disorder clinically characterized by deficits in communication, lack of social interaction and repetitive behaviors with restricted interests.
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