Spike Avalanches Exhibit Universal Dynamics across the Sleep-Wake Cycle.
A unique scale-invariant regime of spike avalanches across all major behaviors.
Neocortex and vocal production in marmosets
Our data provide direct evidence that the ventrolateral prefrontal cortex, a key region for speech control in humans, is also activated during vocal production in a non-human New World primate.
Detecting brain waves communication
Tort et al present a powerful framework for quantifying the level of coupling among simultaneous brain oscillations, which will help elucidating the importance of brain waves communication in cognitive processes.
Motion representation in V1 is mediated by transcortical feedback
Global features of the visual scenery are fed back to lower visual processing units to facilitate the integration of local cues into a global construct.
Revisiting Hebb's postulates
A new analysis framework to address the cell assembly hypothesis at the systems level.
Attractor networks and memory formation and erasure
A unified computational model based on attractor dynamics that accounts for the processes of memory reconsolidation and extinction
Cross-modal responses in the primary visual cortex encode complex objects and correlate with tactile discrimination
The primary visual cortex can engage in meaningful tactile processing
depending on task demand.
Stem cells to neurons: Independent of local niche
Adult neural stem cells (NSCs) could be used to treat nervous system disorders, but does their specification require a local niche? Using adult mouse NSCs, Costa and colleagues show that progression from stem cell to neuron is cell-intrinsic and independent of the local niche.
Forming what-where associations
Tort and colleagues describe a mechanism underlying the emergence of hippocampal firing patterns that represent the conjunction of an item (what) and its location (where).
Speech Graphs Provide a Quantitative Measure of Thought Disorder in Psychosis
Psychosis has various causes, including mania and schizophrenia. Since the differential diagnosis of psychosis
is exclusively based on subjective assessments of oral interviews with patients, an objective quantification of the speech
disturbances that characterize mania and schizophrenia is in order. In principle, such quantification could be achieved by
the analysis of speech graphs. A graph represents a network with nodes connected by edges; in speech graphs, nodes
correspond to words and edges correspond to semantic and grammatical relationships.
OLM interneurons differentially modulate CA3 and entorhinal inputs to hippocampal CA1 neurons
The vast diversity of GABAergic interneurons is believed to endow hippocampal microcircuits with the required flexibility for memory encoding and retrieval. However, dissection of the functional roles of defined interneuron types has been hampered by the lack of cell-specific tools. We identified a precise molecular marker for a population of hippocampal GABAergic interneurons known as oriens lacunosum-moleculare (OLM) cells.
NMDA receptor blockade impairs the muscarinic conversion of sub-threshold transient depression into long-lasting LTD in the hippocampus-prefrontal
cortex pathway in vivo.
Cholinergic fibers from the brainstem and basal forebrain innervate the medial prefrontal cortex (mPFC) modulating neuronal activity and synaptic plasticity responses to hippocampal inputs.