›  Home  ›  research  ›  publication  
Publications

Developmental disruption of recurrent inhibitory feedback results in compensatory adaptation in the Renshaw cell - motor neuron circuit

Here we used the selective expression of the nicotinic cholinergic receptor alpha 2 (Chrna2) in mice to genetically target the vesicular inhibitory amino acid transporter (VIAAT) in Renshaw cells.
 Full Text

Chronic nicotine attenuates behavioral and synaptic plasticity impairments in a streptozotocin model of Alzheimer's disease.

Brain glucose metabolism is altered in sporadic Alzheimer's disease (sAD), whose pathologies are reproduced in rodents by intracerebroventricular (icv) infusion of streptozotocin (STZ) in subdiabetogenic doses.
 Full Text

Selective post-training time window for memory consolidation interference of cannabidiol into the prefrontal cortex: Reduced dopaminergic modulation and immediate gene expression in limbic circuits.

The prefrontal cortex (PFC), amygdala and hippocampus display a coordinated activity during acquisition of associative fear memories.
 Full Text

Dopamine Modulates Delta-Gamma Phase-Amplitude Coupling in the Prefrontal Cortex of Behaving Rats

Dopamine release and phase-amplitude cross-frequency coupling (CFC) have independently been implicated in prefrontal cortex (PFC) functioning.
 Full Text

Selective entrainment of gamma subbands by different slow network oscillations

Respiration-induced oscillations and the theta rhythm modulate different gamma frequencies, suggesting that the brain uses different frequency channels for transferring different types of information.
 Full Text

Thought disorder measured as random speech structure classifies negative symptoms and schizophrenia diagnosis 6 months in advance

This analysis relies mostly on connectedness, a structural feature of speech that is anti-correlated with negative symptoms.
 Full Text

Coupled variability in primary sensory areas and the hippocampus during spontaneous activity

The cerebral cortex is an anatomically divided and functionally specialized structure. It includes distinct areas, which work on different states over time.
 Full Text

Physiology and assessment as low-hanging fruit for education overhaul

Physiology and assessment constitute major bottlenecks of school learning among students with low socioeconomic status.
 Full Text

Chrna2-Martinotti Cells Synchronize Layer 5 Type A Pyramidal Cells via Rebound Excitation

Chrna2-Martinotti cells participate in defined cortical circuits and can synchronize pyramidal cells in a frequency-dependent manner.
 Full Text

Activity-Independent Effects of CREB on Neuronal Survival and Differentiation during Mouse Cerebral Cortex Development

Neuronal survival and morphological maturation depends on the action of the transcription factor calcium responsive element binding protein (CREB), which regulates expression of several target genes in an activity-dependent manner.
 Full Text

On cross-frequency phase-phase coupling between theta and gamma oscillations in the hippocampus

Phase-locking of hippocampal theta and gamma waves has been proposed to support memory formation, but an analysis using robust statistical methods finds no convincing evidence for the phenomenon.
 Full Text

Selective interhemispheric circuits account for a cardinal bias in spontaneous activity within early visual areas

Ongoing brain activity exhibits patterns resembling neural ensembles co activated by stimulation or task performance.
 Full Text


Last entries