"Place and grid cells in a loop: implications for memory function and spatial coding "

Based on the anatomy of the entorhinal-hippocampal circuitry, we constructed a model of place and grid cells organized in a loop to investigate their mutual influence in the establishment of their codes for space.

Publications

Electrophysiological evidence that the retrosplenial cortex displays a strong and specific activation phased with hippocampal theta during paradoxical (REM) sleep"
Aug 18, 2017

It is widely accepted that cortical neurons are similarly more activated during waking and paradoxical sleep (PS, aka REM) than during slow wave sleep (SWS). "

Unveiling Fast Field Oscillations through Comodulation"
Aug 07, 2017

Comodulation analysis unveils four different types of fast LFP activity coupled to theta: two oscillations within the traditional gamma band, HFOs, and spike-leaked activity."

Developmental disruption of recurrent inhibitory feedback results in compensatory adaptation in the Renshaw cell - motor neuron circuit "
Jun 05, 2017

Here we used the selective expression of the nicotinic cholinergic receptor alpha 2 (Chrna2) in mice to genetically target the vesicular inhibitory amino acid transporter (VIAAT) in Renshaw cells. "

Chronic nicotine attenuates behavioral and synaptic plasticity impairments in a streptozotocin model of Alzheimer's disease."
May 13, 2017

Brain glucose metabolism is altered in sporadic Alzheimer's disease (sAD), whose pathologies are reproduced in rodents by intracerebroventricular (icv) infusion of streptozotocin (STZ) in subdiabetogenic doses. "

Selective post-training time window for memory consolidation interference of cannabidiol into the prefrontal cortex: Reduced dopaminergic modulation and immediate gene expression in limbic circuits."
May 12, 2017

The prefrontal cortex (PFC), amygdala and hippocampus display a coordinated activity during acquisition of associative fear memories."

4.10 – Multiple Stages of Memory Formation and Persistence"
Oct 16, 2017

The idea that memories are not made instantly after learning but need to undergo a time-dependent, metabolically active complex consolidation process before they can be stably stored has dominated the neuroscience of learning and memory for decades. "

Short term changes in the proteome of human cerebral organoids induced by 5-MeO-DMT"
Oct 13, 2017

Here we used shotgun mass spectrometry to explore proteomic differences induced by 5-methoxy-N,N-dimethyltryptamine (5-MeO-DMT) on human cerebral organoids. Out of the 6,728 identified proteins, 934 were found differentially expressed in 5-MeO-DMT-treated cerebral organoids."

Sleep, Synaptic Plasticity, and Memory"
Oct 06, 2017

The mechanisms underlying the intimate connection between sleep and learning are becoming increasingly clear. "

Asymmetry of the temporal code for space by hippocampal place cells"
Sep 13, 2017

Here we show that the spike timing of place cells couples to theta phase before major increases in firing rate, anticipating the animal’s entrance into the classical, rate-based place field. "

Place and grid cells in a loop: implications for memory function and spatial coding "
Sep 11, 2017

Based on the anatomy of the entorhinal-hippocampal circuitry, we constructed a model of place and grid cells organized in a loop to investigate their mutual influence in the establishment of their codes for space."

Events

Instituto do Cérebro realiza 2o House Symposium

Com o tema “The Brain in a Nutshell”, o evento é gratuito e aberto à comunidade acadêmica. "

Instituto do Cérebro promove palestra sobre imunidade e processo cognitivo

A palestra é gratuita e voltada para a comunidade acadêmica, especialmente das áreas das biociências, saúde e neurociências."

Palestra de Neurobiologia

A palestra “Neurobiologia da diferenciação sexual” será ministrada pela professora Maria Bernardete Cordeiro de Sousa."

In The Media

Professor do Instituto do Cérebro ganha prêmio de melhor direção em festival de curtas de Goiás

A película “O Fim da História" foi filmada e editada analogicamente usando película super 8 produzida na antiga União Soviética."

PGNeuro está com inscrição aberta para disciplina sobre cognição e linguagem

Os interessados podem se inscrever até 15 de setembro pelo Sistema Integrado de Gestão de Atividades Acadêmicas (Sigaa)."

Professor do Instituto do Cérebro tem filme selecionado para festival de curtas em Goiás

“O Fim da História” está na categoria de ficção e foi filmado e editado por Richardson Leão."


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