"Repertoires of Spike Avalanches Are Modulated by Behavior and Novelty"

Esse artigo mostra em ratos que avalanches neuronais variam através do ciclo sono vigília e refletem em alguma medida os comportamentos dos animais. Detectamos a existência de repertórios complexos de padrões de ativação entre neurônios (avalanches) que são construídas na vigília e reverberadas/repetidas durante o sono. As repetições podem acontecer com intervalos de muitos minutos, se estendendo por várias horas.

Publications

Live Imaging of Adult Neural Stem Cells in Rodents"
Mar 09, 2016

Adult Neural Stem Cells (NSC) in the mouse subventricular zone (SVZ) tracked by retroviral labeling during embryonic development (GFP, green) and identified by the proliferative (Ki67, blue) and astrocyte-specific marker (GFAP, red)."

Impaired theta-gamma coupling in APP-deficient mice"
Feb 26, 2016

The amyloid precursor protein (APP) is critically involved in the pathophysiology of Alzheimer’s disease, but its physiological functions remain elusive. This work shows that lack of APP reduces oscillatory coupling in voltage recordings from specific brain regions, despite not affecting the amplitude of the oscillations, thus pointing to reduced cross-frequency coupling as a functional marker of APP deficiency at the network level."

Hippocampal Respiration-Driven Rhythm Distinct from Theta Oscillations in Awake Mice"
Jan 18, 2016

This work demonstrates that the hippocampus of awake mice produces slow oscillations that are entrained by nasal respiration. The rhythm is close in frequency to, but distinct from, classical theta oscillations. The results suggest that respiration-coupled oscillations aid the exchange of information between olfactory and memory networks. "

Grid Cells and Place Cells: An Integrated View of their Navigational and Memory Function"
Nov 30, 2015

This model explains why MEC lesions can abolish hippocampal phase precession but not place fields."

Impaired Processing in the Primary Auditory Cortex of an Animal Model of Autism"
Nov 24, 2015

Autism is a neurodevelopmental disorder clinically characterized by deficits in communication, lack of social interaction and repetitive behaviors with restricted interests."

A genetic network that suppresses genome rearrangements in Saccharomyces cerevisiae and contains defects in cancers"
May 28, 2016

Gross chromosomal rearrangements (GCRs) play an important role in human diseases, including cancer. The identity of all Genome Instability Suppressing (GIS) genes is not currently known."

Human Brain Expansion during Evolution Is Independent of Fire Control and Cooking"
Apr 25, 2016

What makes humans unique? This question has fascinated scientists and philosophers for centuries and it is still a matter of intense debate. Nowadays, human brain expansion during evolution has been acknowledged to explain our empowered cognitive capabilities. The drivers for such accelerated expansion remain, however, largely unknown. In this sense, studies have suggested that the cooking of food could be a pre-requisite for the expansion of brain size in early hominins. "

Repertoires of Spike Avalanches Are Modulated by Behavior and Novelty"
Mar 28, 2016

Esse artigo mostra em ratos que avalanches neuronais variam através do ciclo sono vigília e refletem em alguma medida os comportamentos dos animais. Detectamos a existência de repertórios complexos de padrões de ativação entre neurônios (avalanches) que são construídas na vigília e reverberadas/repetidas durante o sono. As repetições podem acontecer com intervalos de muitos minutos, se estendendo por várias horas."

Motor Coordination Correlates with Academic Achievement and Cognitive Function in Children"
Mar 15, 2016

The relationship between exercise and cognition is an important topic of research that only recently began to unravel."

Psychosis and the Control of Lucid Dreaming"
Mar 09, 2016

Dreaming and psychosis share important features, such as intrinsic sense perceptions independent of external stimulation, and a general lack of criticism that is associated with reduced frontal cerebral activity."

Events

1º House Symposium

O Instituto do Cérebro (ICe) da Universidade Federal do Rio Grande do Norte (UFRN) realiza nos dias 13 e 14 de novembro, a partir das 8h30, o 1o House Symposium da unidade acadêmica, no Imirá Plaza Hotel, localizado na Via Costeira de Natal-RN."

Simpósio sobre Cognição Imune e Neural está com inscrições abertas

O encontro está previsto para acontecer nos dias 3 e 4 de dezembro, a partir das 8h, no Centro de Convenções do Imirá Plaza Hotel e Convention, localizado na Via Costeira de Natal-RN"

Professor iraniano ministra palestra no ICe

O professor da Shahid Beheshti University (Irã), Mohammad Smail Zibair, ministrará a palestra “Applications of photonic in neuroscience, such as optical fiber biosensor and optogenetics” nesta terça-feira, 22, às 13h30, no auditório do ICe 1."

On The Media

Folha de S. Paulo publica poema de Sidarta Ribeiro

"O assunto é o infinito, falo da vida e da morte e dos tantos atropelamentos que insistem em marcar nosso cotidiano", explica Sidarta."

Tribuna do Norte divulga eleição de Sidarta Ribeiro na Academia de Ciências Latina

A eleição representa uma das mais altas distinções da ciência latino-americana."

Folha de S. Paulo aborda pesquisa que mapeou genes associados ao câncer

O estudo foi realizado pelos professores do Instituto do Cérebro (ICe), Sandro José de Souza, do Instituto Metrópole Digital (IMD), Jorge Estefano Santana de Souza, e o aluno de doutorado do Programa de Pós-Graduação em Bioinformática, André Fonseca, juntamente com especialistas da Universidade da Califórnia (EUA)."


Last entries
2016-03-01| ICe x Zika