"Experience-dependent upregulation of multiple plasticity factors in the hippocampus during early REM sleep"

Sleep is beneficial to learning, but the underlying mechanisms remain controversial. The synaptic homeostasis hypothesis (SHY) proposes that the cognitive function of sleep is related to a generalized rescaling of synaptic weights to intermediate levels, due to a passive downregulation of plasticity mechanisms.

Publications

Graph analysis of verbal fluency test discriminate between patients with Alzheimer’s disease, Mild Cognitive Impairment and normal elderly controls"
Jul 11, 2014

This study reports a graph analysis of data generated by the semantic verbal fluency test by cognitively healthy elderly (NC), patients with Mild Cognitive Impairment – subtypes amnestic (aMCI) and amnestic multiple domain (a+mdMCI) - and patients with Alzheimer’s disease (AD)."

Local Field Potentials in the Gustatory Cortex Carry Taste Information"
Jun 30, 2014

We found that the phase and amplitude of multiple LFP frequencies carry information about stimuli, which have specific time courses after stimulus delivery."

Limiting glutamate transmission in a Vglut2-expressing subpopulation of the subthalamic nucleus is sufficient to cause hyperlocomotion"
Jun 18, 2014

Our results demonstrate that altering the contribuition of a limited population within the STN is sufficiente to achieve results similar to STN lesions and high-frequecy stimulation, but with fewer side effects."

Naps in school can enhance the duration of declarative memories learned by adolescents"
Jun 03, 2014

Here we set out to evaluate the influence of daytime naps on the duration of declarative memories learned in school by students of 10–15 years old."

Astrocyte heterogeneity in the brain: from development to disease"
Mar 25, 2015

In this review, we focused on astrocyte heterogeneity in terms of their morphological, protein expression and functional aspects, and debate in a historical perspective the diversity encountered in glial rogenitors and how they may reflect mature astrocyte heterogeneity."

Specification of excitatory neurons in the developing cerebral cortex: progenitor diversity and environmental influences"
Mar 25, 2015

The mature cerebral cortex harbors a heterogeneous population of glutamatergic neurons, organized into a highly intricate histological architecture. Classically, this mixed population of neurons was thought to be generated sequentially from a seemingly homogenous group of progenitors under the influence of external cues. "

Experience-dependent upregulation of multiple plasticity factors in the hippocampus during early REM sleep"
Mar 17, 2015

Sleep is beneficial to learning, but the underlying mechanisms remain controversial. The synaptic homeostasis hypothesis (SHY) proposes that the cognitive function of sleep is related to a generalized rescaling of synaptic weights to intermediate levels, due to a passive downregulation of plasticity mechanisms."

The onset of data-driven mental archeology"
Aug 13, 2014

How did human consciousness arise, in comparison with that of apes?"

Proliferative Defects and Formation of a Double Cortex in Mice Lacking Mltt4 and Cdh2 in the Dorsal Telencephalon"
Aug 06, 2014

Here we show that the adherens junction proteins afadin and CDH2 are critical for the control of cell proliferation in the dorsal telencephalon and for the formation of its normal laminar structure."

Events

Instituto do Cérebro realiza palestra com pioneiro da Biotecnologia

O Instituto do Cérebro (ICe) realiza a palestra “Oportunidades e limitações para inovação em Biotecnologia no Brasil”, ministrada pelo presidente da Sociedade Brasileira de Biotecnologia (SBBiotec), Luiz Antônio Barreto de Castro, nesta quarta?feira, dia 8, às 15h no Anfiteatro das Aves, do Centro de Biociências (CB), no Campus Central. "

I Congresso de Neurociência e Comportamento

O Instituto do Cérebro (ICe) da Universidade Federal do Rio Grande do Norte (UFRN) realiza o I Congresso Norte-Nordeste de Neurociências e Comportamento (CONNEC) entre os dias 2 e 4 de outubro, durante a V Reunião do Instituto Brasileiro de Neurociências e Comportamento (IBNeC), na cidade de João Pessoa (PB)."

Seminários em Neurociências

Título: "Uso do tratamento repetido com baixas doses de reserpina como um modelo progressivo para a Doença de Parkinson em ratos de diferentes linhagens"."

In The Media

RN TV mostra pesquisa do ICe sobre a importância do sono para consolidar memórias

O programa RN TV, da Inter TV Cabugi, veiculou reportagem na noite dessa quarta-feira, 25, sobre uma pesquisa do Instituto do Cérebro (ICe) que aborda como os sonhos ajudam a consolidar as memórias."

Sidarta Ribeiro esclarece dúvidas da população sobre o sono

O diretor do Instituto do Cérebro (ICe), Sidarta Ribeiro, participou na manhã desta quarta-feira, 25, de uma entrevista sobre o sono no Bom Dia RN, programa da Inter TV Cabugi. O neurocientista falou sobre a sua nova pesquisa "

Dormir e sonhar ajudam a consolidar as memórias

Entre os autores da pesquisa estão Sidarta Ribeiro, do Instituto do Cérebro (ICe) da Universidade Federal do Rio Grande do Norte (UFRN), e Koichi Sameshima, do Hospital Sírio-Libanês e da Universidade de São Paulo (USP)."


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